范武发，研究员，博士生导师，课题组组长。复旦大学药剂学博士，主要从事药物递送研究。担任中国医药教育协会皮肤药学专业委员会委员，Asian Journal of Pharmaceutical Sciences、Chinese Chemical Letters青年编委。获得国家自然科学基金青年科学基金项目资助。
     腾博会游戏大厅_竞彩足球-官网：引进人才，2022年加入腾博会游戏大厅_竞彩足球-官网：，曾在北京大学化学与分子工程学院进行博士后研究工作，从事纳米药物递送研究。

长期从事药物递送研究，通过合成高分子、脂质材料，构建智能纳米药物，实现肿瘤、中枢系统疾病的高效治疗。具体包括纳米药物跨生物屏障递送及机制；纳米药物肿瘤免疫治疗；多肽、蛋白、核酸等大分子药物递送；纳米药物生物学效应。目前发表10余篇SCI论文，其中以通讯作者/第一作者身份在Nature Biomedical Engineering、Advanced Materials、Advanced Drug Delivery Reviews、Nano Today等杂志发表9篇。

腾博会游戏大厅_竞彩足球-官网

1. Aocan Zhao#, Yisi Tang#, Xudong Shi*, Wufa Fan*. Interstitial drug delivery system: Physiological basis and (pre)clinical progress. J Control Release, 2025, 388, 114275. (IF: 11.5)

2. Yisi Tang#, Bao Liu#, Yuting Zhang#, Yuling Liu, Yongzhuo Huang*, Wufa Fan*. Interactions between nanoparticles and lymphatic systems: Mechanisms and applications in drug delivery. Adv Drug Deliv Rev, 2024, 209, 115304. (IF: 17.6)

3. Wufa Fan#, Jiajia Xiang#, Qiuyu Wei#, Yisi Tang#, Ying Piao, Shiqun Shao, Zhuxian Zhou*, Jianbin Tang, Zi-Chen Li*, Youqing Shen*. Role of micelle size in cell transcytosis-based tumor extravasation, infiltration, and treatment efficacy. Nano Lett, 2023, 23, 3904-3912. (IF: 9.6)

4. Wufa Fan#, Qiuyu Wei, Jiajia Xiang, Yisi Tang, Quan Zhou, Yu Geng, Yanpeng Liu, Rui Sun, Lei Xu, Guowei Wang, Ying Piao, Shiqun Shao*, Zhuxian Zhou, Jianbin Tang, Tao Xie, Zichen Li*, Youqing Shen*. Mucus penetrating and cell-binding polyzwitterionic micelles as potent oral nanomedicine for cancer drug delivery. Adv Mater 34(16):e2109189. (IF=32.086)

5. Wufa Fan#, Haixia Peng, Zhou Yu, Luting Wang, Haisheng He, Yuhua Ma, Jianping Qi, Yi Lu, Wei Wu*. The long-circulating effect of pegylated nanoparticles revisited via simultaneous monitoring of both the drug payloads and nanocarriers. Acta Pharm Sin B 12(5):2479-2493. (IF=14.903)

6. Siqin Chen#, Yin Zhong#, Wufa Fan#, Jiajia Xiang#, Guowei Wang, Quan Zhou, Jinqiang Wang, Yu Geng, Rui Sun, Zhen Zhang, Ying Piao, Jianguo Wang, Jianyong Zhuo, Hailin Cong, Haiping Jiang, Jun Ling, Zichen Li, Dingding Yang, Xin Yao, Xiao Xu, Zhuxian Zhou, Jianbin Tang, Youqing Shen*. Enhanced tumour penetration and prolonged circulation in blood of polyzwitterion-drug conjugates with cell-membrane affinity. Nat Biomed Eng 5(9):1019-1037. (IF=29.234, ESI)

7. Yisi Tang#, Wufa Fan#, Guihua Chen, Meng Zhang, Xueping Tang, Hairui Wang, Pengfei Zhao, Qin Xu, Zhibing Wu*, Xiaoxi Lin, Yongzhuo Huang*. Recombinant cancer nanovaccine for targeting tumor-associated macrophage and remodeling tumor microenvironment. Nano Today 40:101244. (IF=18.962)

8. Wufa Fan#, Zhou Yu#, Haixia Peng, Haisheng He, Yi Lu, Jianping Qi, Xiaochun Dong, Weili Zhao, Wei Wu*. Effect of particle size on the pharmacokinetics and biodistribution of parenteral nanoemulsions. Int J Pharm 586:119551. (IF=5.875)

9. Zhou Yu#, Wufa Fan#, Luting Wang, Haisheng He, Yongjiu Lv, Jianping Qi, Yi Lu, Wei Wu*. Slowing down lipolysis significantly enhances the oral absorption of intact solid lipid nanoparticles. Biomater Sci 7(10):4273-4282. (IF=6.183)